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  • Assembly of 809 whole mitochondrial genomes with clinical, imaging, and fluid biomarker phenotyping

     

    Authors: Perry Ridge, Mark Wadsworth, Justin Miller, RC Green, Andrew Saykin, Alzheimer's Disease Neuroimaging Initiative, John SK Kauwe

     

    Alzheimer's Disease and Dementia

    Article

     

    January, 2018

    1 citation

    1 news mention

    10 tweets

     

  • Novelty of Approach

     

    -Assembled and called variants on 809 whole mitochondrial genomes

    -Annotated variants with MITOMAP

    -Used Phy-Mer to annotate mitochondrial haplotype

     

     

  • Results

     

    -Established a mitochondrial haplotype database

     

  • Implications

     

    -Allows for more researchers to study the risks of mitochondrial genetics on Alzheimer's disease