Assembly of 809 whole mitochondrial genomes with clinical, imaging, and fluid biomarker phenotyping
Authors: Perry Ridge, Mark Wadsworth, Justin Miller, RC Green, Andrew Saykin, Alzheimer's Disease Neuroimaging Initiative, John SK Kauwe
Alzheimer's Disease and Dementia
January, 2018
1 citation
10 tweets
Novelty of Approach
-Assembled and called variants on 809 whole mitochondrial genomes
-Annotated variants with MITOMAP
-Used Phy-Mer to annotate mitochondrial haplotype
Results
-Established a mitochondrial haplotype database
Implications
-Allows for more researchers to study the risks of mitochondrial genetics on Alzheimer's disease